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Saccharomyces boulardii CNCM I-745
11 Meta-analysis
Source: Szajewska H, Kołodziej M. Systematic review with meta-analysis: Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea.
Results:
Studies reviewed
- 21 studies
- 12 studies were placebo controlled
- 15 trials in adults
- 6 trials in children
- 4780 participants (2441 treated with S. boulardii and 2339 in the control group)
Overall there was a reduction in the risk of antibiotic associated diarrhea in both children and adults of 53%.
Antibiotic susceptibility of S. boulardii CNCM I-745 versus other probiotic strains
The only probiotic strain proven resistant to 16 of the most commonly prescribed oral antibiotics
Saccharomyces boulardii CNCM I-745
Natural and unique yeast
Learn more about our yeast and its characteristics:
- 10x larger cell size for increased coverage.
- Viable at lower pH to survive gastric digestion.
- Eukaryote, no risk of genetic transfer of antibiotic resistence.
- Reaches colon in active state.
- Enhances production of short chain fatty acids (preferred source for enterocytes).
- Increases brush border enzymes (lactase, sucrase, maltase).
- Stimulates increased seccretory igA to support a healthy immune system.
- Does not lead to permanent intestinal colonizations.
S. boulardii is recommended by:
- the World Gastroenterology Organisation (WGO)
- the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN)
- the American Gastroenterology Association (AGA)
Microbiota Institute
Launched in 2017, the Biocodex Microbiota Institute is a non-promotional hub of knowledge dedicated to microbiota providing scientific news and data.
